As i had 19's,20's and 22's i can say tthat you can feel difference in weight of different wheels.
My 20's were 3,5kg heavier (each) than stocks and there more effort needed for stopping...........same for acceleration.
22's are just 1 kg heavier (Enkei's) than stockies (incl.tyres) and both braking and accelerating is pretty much same as with stockies.
There is no win-win situation in this game.............as i have 20 Klugers in my work shed i can say there is difference in performance between models.
Best acceleration..........KXR AWD
Best handling KXS AWD.
2WD are too "boaty",AWD's handle much better.